Saida Oubraim, PhD
Postdoctoral Fellow
Electrophysiology and Cellular Neuroscience
Contact Information
1021 Main Street
Buffalo, NY 14203-1016
Phone: (716) 887-2231
Email: saidaoub@buffalo.edu
Primary Research Areas
Fetal alcohol spectrum disorder, serotonin system, social behavior, synaptic transmission and plasticity.
Representative and Recent Publications
Kwarteng F, Wang R, Micov V, Hausknecht KA, Turk M, Ishiwari K, Oubraim S, Wang AL, Richards JB, Haj-Dahmane S, Shen RY. Adolescent chronic unpredictable stress leads to increased anxiety and attention deficit/hyperactivity-like symptoms in adulthood. Psychopharmacology (Berl). 2022 Dec;239(12):3779-3791. doi: 10.1007/s00213-022-06242-1. Epub 2022 Nov 9. PMID: 36348027.
Oubraim S, Wang R, Hausknecht K, Kaczocha M, Shen RY, Haj-Dahmane S. Prenatal ethanol exposure causes anxiety-like phenotype and alters synaptic nitric oxide and endocannabinoid signaling in dorsal raphe nucleus of adult male rats. Transl Psychiatry. 2022 Oct 10;12(1):440. doi: 10.1038/s41398-022-02210-7. PMID: 36216807; PMCID: PMC9550821.
Fauzan M, Oubraim S, Yu M, Glaser ST, Kaczocha M, Haj-Dahmane S. Fatty Acid-Binding Protein 5 Modulates Brain Endocannabinoid Tone and Retrograde Signaling in the Striatum. Front Cell Neurosci. 2022 Jul 7;16:936939. doi: 10.3389/fncel.2022.936939. PMID: 35875351; PMCID: PMC9302024.
Wang R, Martin CD, Lei AL, Hausknecht KA, Turk M, Micov V, Kwarteng F, Ishiwari K, Oubraim S, Wang AL, Richards JB, Haj-Dahmane S, Shen RY. Prenatal ethanol exposure impairs sensory processing and habituation to visual stimuli, effects normalized by enrichment of postnatal environmental. Alcohol Clin Exp Res. 2022 May;46(5):891-906. doi: 10.1111/acer.14818. Epub 2022 Apr 18. PMID: 35347730; PMCID: PMC9122102.
Oubraim S, Wang R, Hausknecht KA, Shen RY, Haj-Dahmane S. Tonic Endocannabinoid Signaling Gates Synaptic Plasticity in Dorsal Raphe Nucleus Serotonin Neurons Through Peroxisome Proliferator-Activated Receptors. Front Pharmacol. 2021 Jun 28;12:691219. doi: 10.3389/fphar.2021.691219. PMID: 34262460; PMCID: PMC8273699.
Wang R, Martin CD, Lei AL, Hausknecht KA, Ishiwari K, Oubraim S, Wang AL, Richards JB, Haj-Dahmane S, Shen RY. Moderate prenatal ethanol exposure leads to attention deficits in both male and female rats. Alcohol Clin Exp Res. 2021 May;45(5):1122-1135. doi: 10.1111/acer.14599. Epub 2021 Apr 16. PMID: 33730380.
Wang R, Hausknecht KA, Gancarz-Kausch AM, Oubraim S, Shen RY, Haj-Dahmane S. Cocaine self-administration abolishes endocannabinoid-mediated long-term depression of glutamatergic synapses in the ventral tegmental area. Eur J Neurosci. 2020 Dec;52(11):4517-4524. doi: 10.1111/ejn.14980. Epub 2020 Sep 30. PMID: 32959420; PMCID: PMC7775329.