Since X-rays were discovered more than a century ago, triggering a revolution in medical imaging, clinicians have sought more powerful ways to "see" into the human body. Now, with a $1.1 million grant from the John R. Oishei Foundation, researchers in the University at Buffalo's Institute for Lasers, Photonics and Biophotonics are turning their expertise in nanomedicine to the development of new, nanoparticle-based multi-probe systems, launching a new generation of medical imaging.