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Inadequate sleep linked to diabetes
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“This study supports growing evidence of the association of inadequate sleep with adverse health issues.”
To the many problems associated with lack of sleep—moodiness, memory problems, difficulty concentrating—add the risk of developing diabetes.
A UB study shows that people who sleep less than six hours a night during the work week are 4.5 times more likely to have elevated levels of blood sugar than those who slumber six to eight hours.
The findings were presented last week at the American Heart Association’s 49th annual Conference on Cardiovascular Disease Epidemiology and Prevention.
“Impaired fasting glucose—a reading higher than 100—is known as pre-diabetes, which is a precursor to type 2 diabetes,” said Lisa Rafalson, a National Research Service Award Fellow in the Department of Family Medicine, School of Medicine and Biomedical Sciences, and first author on the study.
“In fact, about 25 percent of people who have impaired fasting glucose will at some point develop type 2 diabetes, which is associated with many complications, including heart disease and premature death.” Rafalson also is a research assistant professor is the Department of Social and Preventive Medicine, School of Public Health and Health Professions.
Rafalson’s findings were based on data from an average six-year follow-up of participants who initially took part in the Western New York Health Study, conducted from 1996-2001. The 91 persons with normal fasting glucose levels at baseline who developed pre-diabetes by their follow-up exam were matched to persons from the study who had maintained normal glucose levels, who served as controls.
Participants were placed into three groups based on the average daily amount of sleep they reported receiving from Sunday through Thursday: short-sleepers—those who reported less than six hours of sleep nightly; long-sleepers, who reported sleeping more than eight hours nightly; and a reference group who slept six to eight hours a night.
Results showed that short-sleepers had a significantly increased risk of progressing from normal glucose levels to pre-diabetes, compared to those who slept six to eight hours nightly. Sleeping an average of more than eight hours a night had no significant effect on glucose levels, results showed.
“This study supports growing evidence of the association of inadequate sleep with adverse health issues,” said Rafalson. She suggested that during annual “well” visits, physicians should discuss sleep habits with their patients, along with diet and exercise, and other lifestyle issues that are important to long-term health.
“Genetic susceptibility is always a possible explanation for this finding,” Rafalson noted, “but it is more likely that pathways involving hormones and the nervous system are involved in the impaired-sleep/fasting glucose association.
“We hope our findings will generate more research into this complex relationship between sleep and illness,” she said.
Additional authors on the study are Richard P. Donahue, Michael LaMonte, Joan Dorn, Maurizio Trevisan, Saverio Stranges and Jacek Dmochowski. All authors are current or former members of the Department of Social and Preventive Medicine.
The study was funded by the National Institutes of Health.
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