The current available treatment options prioritize symptom management and do not target underlying causes of the disease. Since the severity varies between each patient, we are not sure if one treatment will work for everyone, or multiple treatment options are needed that can target different mutations. This is what makes it challenging for researchers studying FOXG1 syndrome and finding treatment(s) that would work. Together with the FOXG1 Research Foundation, we have successfully developed different Foxg1 mutant mouse lines and iPSC lines that resemble human Foxg1 patient conditions – representing a spectrum of FOXG1 phenotypes.
Our mission is to translate new discoveries from the lab to clinical trials and ultimately, develop better treatment options that are both safe and effective for young patients who are impacted by FOXG1 syndrome.