University at Buffalo endocrinologists have shown for the first time that the concentration of a proinflammatory compound known as MIF is increased in the blood plasma of the obese, and that metformin, a standard medicine prescribed for diabetes, suppresses its formation.
A decade ago, high school students who aspired to life sciences careers foresaw a future full of pipettes and beakers; today, high school students with similar aspirations are honing their skills at the computer as much as at the lab bench. Toward that end, nine high school students will learn the basics of bioinformatics -- the interface where life science meets computational science -- at the University at Buffalo's Summer High School Workshop in Computational Science.
Scientists at the University at Buffalo's Institute for Lasers, Photonics and Biophotonics, working with colleagues at the Roswell Park Cancer Institute (RPCI), have developed a non-release, nanoparticle drug delivery system for photodynamic cancer therapy.
The University at Buffalo School of Medicine and Biomedical Sciences is one of 10 medical schools nationwide selected by the American Medical Association (AMA) to participate in a new initiative aimed at integrating medical professionalism issues into the medical-school curriculum.
Corticosteroids, drugs that simultaneously deliver powerful therapeutic effects and potentially severe adverse effects, cause a remarkably complex "domino effect" of genomic changes, according to a landmark paper by University at Buffalo pharmaceutical scientists.
Molecular biologists at the University at Buffalo have discovered a novel way to inhibit the replication of poxviruses, the group that includes smallpox virus, by interfering with messenger RNA synthesis necessary for the viruses to reproduce in a host organism.
Researchers in the University at Buffalo's Research Institute on Addictions will be gauging the prevalence of problem gambling among adolescents and young adults in a study funded by a new four-year, $1,827,000 grant from the National Institute of Mental Health.
Results from a case-control study on alcohol consumption and breast cancer risk conducted by epidemiologists at the University at Buffalo indicate that premenopausal women who usually have more than two drinks per occasion have an 80 percent greater risk of developing breast cancer than women who drink less on each occasion.
Geographers and epidemiologists from the University at Buffalo, using life-course data from a cohort of breast cancer patients and controls in Western New York and geographic information systems (GIS) technology, have shown that women who developed breast cancer before menopause tend to cluster based on where they were born and where they lived when they began menstruating.