UB EXPERTS
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FEATURED EXPERT
Dr. Ionita is assistant professor in the departments of Biomedical Engineering and Neurosurgery and director of the Endovascular Devices and Imaging lab at UB's Canon Stroke & Vascular Research Center. His research focuses on improvement of endovascular image guided interventions and encompasses three major components: medical imaging, computer programming and endovascular device development.
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Cardiopulmonary physiology; Cardiovascular Disease; Metabolism; Molecular and Cellular Biology; Molecular Basis of Disease; Research Lab; Signal
Low dose Biophotonics Therapy; Stem cells in regenerative medicine; TGF beta Biology
Utilization of pharmacokinetic and pharmacodynamic analyses and mathematical modeling to guide the discovery and development of new immunotherapies for cancer and autoimmunity
Immunotherapy: Develop lipid mediated tolerance strategies to overcome unwanted immune responses (protein and antibody therapeutics, allergies, autoimmune conditions and gene therapy)
Protein delivery and immunotherapy: Adopts an interdisciplinary approach of biophysics/bioengineering, pharmacokinetic and pharmacodynamic and immunology.
Protein formulation: Physicochemical and analytical methods of assessing protein structure, function, and stability in developing improved dosage forms
Biomedical Imaging; Cardiac pharmacology; Drug Development; Drug Discovery; Electrophysiology; Ion channel kinetics and structure; Ion Transport; Membrane Biophysics; Membrane Transport (Ion Transport); Molecular and Cellular Biology; Molecular Basis of Disease; Neurobiology; Neuroscience; Stem Cells; Translational Research
Computer vision; machine learning; multimodal data analytics; pattern recognition; large-scale visual search and mining; big data analytics
Health information technology and informatics, healthcare systems modeling, design and evaluation of healthcare interventions on patient and organizational outcomes, process and product quality improvement, simulation modeling and applications
Physical ergonomics, biomechanics, occupational safety and health, workplace wellness, designing workplace accommodations for the obese and older populations
Human-Machine Interactions, Cognitive Engineering, Driver Behavior and Safety, Human Factors in Healthcare
Biodegradable functional polymers and nanostructures, new drug delivery systems, synthetic materials for tissue engineering.
Bioinformatics tools to advance personalized medicine; improve quantity and quality of data for medical research; lower barriers to entry for clinicians; advanced machine learning and data analytic methods
Ascertainment and recruitment of human populations, neuroscience, genetics, ophthalmology, epidemiology, statistical genetics and molecular biology.
Applied orthopedic biomechanics, Corrosion and biocompatibility of metallic orthopedic biomaterials
To develop multiscale mathematical and computational models to enhance understanding of the mechanisms governing tissue remodeling and damage as a result of diseases and infections and to simulate the treatment of those conditions to improve human health.
Computational chemistry and materials science; virtual high-throughput and Big Data; machine learning; electronic structure theory and methods; quantum effects in catalysis and materials; rational design
Investigation of low-dose computed tomography protocols and their effect on quantitative lung assessment and imaging processing algorithm development for longitudinal analysis of solid tumors.
Bioengineering; Materials
Biomedical Imaging; Cardiovascular Disease; Diagnostic Radiology; Image Processing and Analysis; Imaging Informatics; Neurosurgery; Radiological Physics; Vascular and Interventional Radiology; Vision science
Runs BSL3 Lab Facility; Microbial Pathogenesis; Microbiology; Molecular and Cellular Biology; Protein Function and Structure; Viral Pathogenesis; Virology
Bioengineering, Rehabilitation Robotics, Prosthetic Devices, Cable-Actuated Mechanisms, Intelligent Wheelchairs
Heterogeneous catalysis; nanoparticle synthesis and surface science, and the application of such catalysts to environmental processes
Novel membrane materials for CO₂ capture from flue gas and syngas; antifouling membranes for water purification; understanding of polymer structure/property correlations in thin films
Development of nanomedicine approaches to meet unmet needs in treating, diagnosing or preventing disease; Nanomedicine; Phototherapy
DNA Replication, Recombination and Repair; Drug Discovery; Emergent Pathogens; Genome Integrity; Infectious Disease; Microbiology; Molecular and Cellular Biology; Molecular genetics; Virology
Biomedical engineering; hemodynamics and vascular biomechanics; advanced laser flow diagnostics; computational fluid dynamics
To characterize lipid-lipid and lipid-protein interactions that are relevant for lipid regulation and cell signaling processes in cancer and liver disease.
Bioinorganic chemistry: Magnetic resonance imaging contrast agents based on iron, cobalt or nickel; bimodal (fluorescent) probes; ligand synthesis, self-assembled multinuclear iron complexes for imaging and drug delivery; yeast cell labeling with inorganic complexes
Bacterial infection in chronic obstructive pulmonary disease (COPD); Haemophilus influenzae pathogenesis; Microbial pathogenesis within the respiratory tract; Moraxella catarrhalis pathogenesis; Vaccine development
Modeling and Prediction of Human Behavior
Relationship between the neurochemical and behavioral effects of drugs, primarily those used to treat neuropsychiatric illnesses. This work includes the study of noradrenergic mechanisms in the actions of antidepressant drugs and of cyclic nucleotide phosphodiesterases as potential targets for novel antidepressant, anxiolytic, and memory‐enhancing drugs.
LOC (lab-on-a-chip); MicroTAS (Micro Total Analysis Systems); BioMEMS (Bio Micro Electro Mechanical Systems); SANS (Sample-to-Answer Nano/microfluidic Systems); nanobiosensors for bio/chemical/environmental applications; world-to-chip interfacing and packaging; single cell manipulation, sorting, and detection; microvalves; micropumps; microfluidic
High-resolution and large-scale expression profiling of pathological proteomes;
Biomedical Engineering; Biophysical Modeling; Computational Biology; Drug Development; Drug Discovery; Electrophysiology; Ion channel kinetics and structure; Ion Transport; Membrane Biophysics; Membrane Transport (Ion Transport); Neuroscience; Stem Cells
Polymer and organic materials chemistry: synthesis of multicomponent polymers, self-assembly and nanomaterials, chemical upcycling of polymers
Artificial Intelligence; Bioinformatics; Biomedical Informatics; Biophysical Modeling; Computational Biology; Computational Chemistry; Computational Drug Discovery; Drug Design; Drug Development; Drug Discovery; Genomics and proteomics; Molecular and Cellular Biology; Nanotechnology; Protein Folding; Protein Function and Structure; Proteomics; Structural Biology; Translational Research
Neurological Surgery, Neuroradiology, Aneurysm, Stroke, Thrombectomy, Cancer, Neurovascular Imaging, Neurovascular Surgery, Vascular
Autoimmunity; Dermatology; Gene Expression; Genomics and proteomics; Immunology
Biophysical investigations of the pharmaceutical properties of drug carrier complexes; pharmacokinetic and pharmacodynamic analysis to probe mechanisms behind the therapeutic effects of drug carriers; proteomic analysis based on liquid chromatography/mass spectrometry; drug-mediated interdiction of specific of tumor-stromal interactions to modulate tumor vascular permeability and antibody/drug carrier deposition in tumors
STEM education; social justice; social problems; sociology of education, race & ethnic relations, social networks & social capital; qualitative research methods; social media
Novel physical, chemical, and biological detection using micro and nano mechanical sensors and electrical power delivery using the single wire concept
Bio-Inspired Analog Visual Systems; Bioinstrumentation; Integrated Sensors; Neuromorphic Visual Processing Systems
Molecular recognition, crystallization, self-assembly, interfacial phenomena, biomimetics, formulations. Materials: polymers (polyelectrolytes, biopolymers, associating polymers, block copolymers), surfactants, biomaterials, supramolecules, dyes, colloidal particles, crystals, cosolvents. Techniques: rheology, small-angle X-ray (SAXS) and neutron (SANS) scattering, static and dynamic light scattering, UV-vis and fluorescence spectroscopy, conductivity, vapor pressure osmometry (VPO), surface free energy, electron spectroscopy for chemical analysis (ESCA), atomic force microscopy (AFM). Broad impact: products and processes that improve the quality of life (health, environment).
Engineering principles and design concepts to develop novel therapeutics and diagnostics (theranostics) for the diagnosis and treatment of cancer and other deadly diseases.
Optical and ultrasonic imaging techniques to meet needs in cancer and neurological research; Sensors, Medical Imaging, Photoacoustics
Compressed sensing; magnetic resonance imaging; image reconstruction
Microbiology, Oral Biology, Periodontics