Research Facilities

The Clinical Research Center (CRC) — located in the UB Clinical and Translational Research Center — is a seven-room, full-service outpatient research clinic. As an investigator conducting studies in the CRC, you can expect a wide range of equipment and services to support your work.  

Our instrument laboratory provides training and consultation services for researchers whose work involves flow cytometry, confocal microscopy and gel-documentation.

Features state-of-the-art imaging equipment dedicated to clinical and translational research, including MRI, CT and PET/CT scanners.

Electron microscopy is provided by the Department of Pathology and Anatomical Sciences. Faculty, trainees, students and other researchers visit this facility when their work requires technology for high resolution thin section work and biological specimen preparation.

This facility offers high-throughput, next-generation sequencing on two Illumina HiSeq2500 and MiSeq platforms. We have expertise in whole-genome, exome, epigenetic and microbiome sequencing, and we work in conjunction with a team of bioinformaticists to help facilitate rapid analysis and algorithm deployment, as well as data storage and management. 

This facility focuses on:

• Ultra-sensitive quantification of small-molecule analytes such as drugs, metabolites and biomolecules
• Comprehensive protein expression profiling and differential proteome analysis
• Ultra-sensitive quantification of proteins/peptides

This facility provides expertise in toxicology for basic and applied research projects. It maintain an analytical toxicology laboratory and offer a wide variety of analytical techniques to solve complicated research problems.

We help investigators generate induced pluripotent stem cells from human skin fibroblasts using lentiviral vectors delivering five reprogramming factors (Oct4, Sox2, Klf4, c-Myc and Nanog).

Researchers at UB use this facility for innovative studies. Services include training courses on stem cell culture and consultation on the differentiation of stem cells to cell types.

This facility analyzes the engraftment of a variety of stem cells in vivo, the effects of genetic modification of stem cells on engraftment and stem cell function, and the behavioral consequences of neural engraftment.

We are a resource for epigenomic analysis of stem cells. Our facility functions interactively with other stem cell facilities at UB to characterize stem cells and their differentiated progeny.

UB offers a multidisciplinary cleanroom with class 1000 space and class 100 working areas – a facility well-equipped for electronic device research, processing and development, materials characterization, microfabrication and other processes.  

The Materials Characterization Lab offers equipment for liquid, powder, surface and bulk materials characterization, as well as expert analytical services for product quality assurance, failure analysis, and forensic evaluations.

The Digital Manufacturing Lab houses a variety of high-definition 3D printing/ additive manufacturing technologies, software and capabilities for modeling and digital design, manufacturing and analysis.